Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.8
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Calories
10
 
Total Fat
1.3 g
2%*
Polyunsaturated Fat
1 g
Monounsaturated Fat
<0.5 g
Evening Primrose Oil(Oenothera biennis) (Seed) (Cold-Pressed, Hexane-Free)
1.3 g (1,300 mg)
Gamma Linolenic Acid (GLA)
120 mg

Top Medical Research Studies

We examined the latest insights into herbal therapies for rheumatoid arthritis, including evening primrose oil. Our analysis included 22 studies, revealing moderate evidence suggesting that gamma linolenic acid (GLA), found in evening primrose oil, may ease pain and disability related to RA.

However, while some benefits were noted, the evidence remains mixed and the risk of side effects should not be overlooked. More comprehensive studies are needed to firmly establish its effectiveness for RA treatment.
Read More
7
Evening primrose oil shows symptom relief
We explored the impact of evening primrose oil (EPO) on rheumatoid arthritis (RA) in a double-blind, placebo-controlled study involving 49 patients. Participants took EPO or EPO combined with fish oil, with the aim of reducing reliance on non-steroidal anti-inflammatory drugs (NSAIDs).

After 12 months, those on EPO noted significant improvements and were able to cut back on their NSAIDs. However, once they switched to placebo, they relapsed, revealing that while EPO may improve symptoms, it doesn't change the underlying disease. Thus, it appears evening primrose oil can help manage RA symptoms and lessen NSAID use, but it doesn’t modify the disease itself.
Read More
4
Evening primrose oil shows mild effect
We looked into how evening primrose oil might help relieve symptoms of rheumatoid arthritis in a study involving 40 patients over six months. Patients were split into two groups: one received evening primrose oil, while the other got a placebo.

While there were mild improvements in morning stiffness for those taking evening primrose oil, olive oil actually showed a more significant reduction in pain over time. Therefore, evening primrose oil may offer some benefits, but olive oil revealed notable advantages that shouldn't be overlooked.
Read More

Most Useful Reviews

9
Pain reduction noted
Excellent evening primrose oil effectively reduces pain associated with rheumatoid arthritis.
Read More
6
Supports skin health
12 people found this helpful
Affordable products, health products or to insist on eating only effective Evening primrose oil has numerous advantages for women. It plays a role in treating hypertension, preventing cerebral thrombosis, and lowering lipids. It also aids various types of inflammation, including rheumatoid arthritis. This evening primrose oil contains 1300 mg of oil with natural gamma-linolenic acid (GLA), an omega-6 fatty acid. GLA is beneficial for maintaining skin barrier function and supports healthy vascular systems. It may also provide nutritional support for mild discomfort related to premenstrual syndrome and balances hormones, making it an affordable nutritional oil.
Read More
7
Useful for menopause
4 people found this helpful
I bought it for the first time to prevent menopausal symptoms, particularly night sweats. Combined with omega supplements, these large but easily swallowable capsules are of good quality. I consume two monthly, which suffices for my needs. They help to relieve inflammation and support health, particularly beneficial for rheumatoid arthritis.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7
  • All Researches
8
We examined how supplementation with marine omega-3 fatty acids and evening primrose oil (rich in GLA) could help relieve rheumatoid arthritis symptoms in a randomized trial of 60 patients.

After 12 weeks, those taking either fish oil alone or in combination with evening primrose oil showed remarkable improvements in joint pain and disease activity compared to those who received no supplements.

This suggests that these oils may significantly benefit people dealing with the inflammation and discomfort of rheumatoid arthritis.
Read More
8
EPO shows promise for arthritis
We investigated the potential benefits of evening primrose oil (EPO) on rheumatoid arthritis, focusing on its anti-inflammatory and anti-oxidant properties. Using an animal model, we found that EPO normalized body weight and reduced inflammatory markers in rats with arthritis.

Moreover, it showed improvement in joint health and decreased inflammation when used alone or alongside traditional pain relievers like aspirin and celecoxib. While these findings are promising, it’s essential to note that the impact is still being explored in more extensive studies.
Read More
We explored the effects of evening primrose oil and its key components, long-chain fatty alcohols (LCFAs), on inflammation. In our tests, these compounds demonstrated a remarkable ability to reduce inflammatory responses in lab-based mouse macrophages, decreasing the production of factors that drive inflammation.

While evening primrose oil has traditionally been used for conditions like rheumatoid arthritis, the study highlighted that these LCFAs specifically target gene expressions involved in inflammation. Though the findings are promising, more research is needed to see how this translates to human health outcomes.
Read More
We examined the latest insights into herbal therapies for rheumatoid arthritis, including evening primrose oil. Our analysis included 22 studies, revealing moderate evidence suggesting that gamma linolenic acid (GLA), found in evening primrose oil, may ease pain and disability related to RA.

However, while some benefits were noted, the evidence remains mixed and the risk of side effects should not be overlooked. More comprehensive studies are needed to firmly establish its effectiveness for RA treatment.
Read More
7
Evening primrose oil shows symptom relief
We explored the impact of evening primrose oil (EPO) on rheumatoid arthritis (RA) in a double-blind, placebo-controlled study involving 49 patients. Participants took EPO or EPO combined with fish oil, with the aim of reducing reliance on non-steroidal anti-inflammatory drugs (NSAIDs).

After 12 months, those on EPO noted significant improvements and were able to cut back on their NSAIDs. However, once they switched to placebo, they relapsed, revealing that while EPO may improve symptoms, it doesn't change the underlying disease. Thus, it appears evening primrose oil can help manage RA symptoms and lessen NSAID use, but it doesn’t modify the disease itself.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 10 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Pain reduction noted
Excellent evening primrose oil effectively reduces pain associated with rheumatoid arthritis.
Read More
6
Supports skin health
12 people found this helpful
Affordable products, health products or to insist on eating only effective Evening primrose oil has numerous advantages for women. It plays a role in treating hypertension, preventing cerebral thrombosis, and lowering lipids. It also aids various types of inflammation, including rheumatoid arthritis. This evening primrose oil contains 1300 mg of oil with natural gamma-linolenic acid (GLA), an omega-6 fatty acid. GLA is beneficial for maintaining skin barrier function and supports healthy vascular systems. It may also provide nutritional support for mild discomfort related to premenstrual syndrome and balances hormones, making it an affordable nutritional oil.
Read More
7
Useful for menopause
4 people found this helpful
I bought it for the first time to prevent menopausal symptoms, particularly night sweats. Combined with omega supplements, these large but easily swallowable capsules are of good quality. I consume two monthly, which suffices for my needs. They help to relieve inflammation and support health, particularly beneficial for rheumatoid arthritis.
Read More
9
Improves skin and pain
Evening primrose oil is essential for women, especially during menstruation. It alleviates pain, improves my skin condition, and helps regulate blood pressure while treating rheumatoid arthritis, diabetic neuropathy, and psoriasis.
Read More
7.5
Effective for inflammation
The quality of Super Primrose NOW Foods is excellent, lasting me four months. Its beneficial ingredients and omega-3 contribute to inflammation relief. It assists with PMS and menopause symptoms, which is valuable for all ages post-menses. Additionally, it may alleviate symptoms of rheumatoid arthritis. It is advisable to take primrose oil for at least three months to notice effects, and I plan to reorder.
Read More

Frequently Asked Questions

7.5
Effective for inflammation
The quality of Super Primrose NOW Foods is excellent, lasting me four months. Its beneficial ingredients and omega-3 contribute to inflammation relief. It assists with PMS and menopause symptoms, which is valuable for all ages post-menses. Additionally, it may alleviate symptoms of rheumatoid arthritis. It is advisable to take primrose oil for at least three months to notice effects, and I plan to reorder.
9
Pain reduction noted
Excellent evening primrose oil effectively reduces pain associated with rheumatoid arthritis.
7.5
Mitigates menopausal symptoms
I purchased this to combat menopausal symptoms like nightly hot flashes. Along with omega, these large gelatin capsules are easy to take. The quality seems promising; I hope for health benefits. I take two a month, sufficient for my needs. This supplement is particularly useful for rheumatoid arthritis and may help improve heart health and reduce bad cholesterol.
7.5
Reduces inflammation
Though I haven’t taken this supplement long, I’ve had good results in the past. My rheumatoid arthritis has improved; the inflammation in my joints is reduced. I also hope it will have heart benefits, as I am more prone to heart disease.
7
Useful for menopause
4 people found this helpful
I bought it for the first time to prevent menopausal symptoms, particularly night sweats. Combined with omega supplements, these large but easily swallowable capsules are of good quality. I consume two monthly, which suffices for my needs. They help to relieve inflammation and support health, particularly beneficial for rheumatoid arthritis.
7.5
May relieve arthritis
Evening primrose oil may relieve eczema symptoms and minimize Tretinoin side effects. It might also improve symptoms of menopause, PMS, and breast pain. Furthermore, it could enhance lipid levels and improve symptoms of rheumatoid arthritis and diabetic neuropathy pain.
6
Supports skin health
12 people found this helpful
Affordable products, health products or to insist on eating only effective Evening primrose oil has numerous advantages for women. It plays a role in treating hypertension, preventing cerebral thrombosis, and lowering lipids. It also aids various types of inflammation, including rheumatoid arthritis. This evening primrose oil contains 1300 mg of oil with natural gamma-linolenic acid (GLA), an omega-6 fatty acid. GLA is beneficial for maintaining skin barrier function and supports healthy vascular systems. It may also provide nutritional support for mild discomfort related to premenstrual syndrome and balances hormones, making it an affordable nutritional oil.
8
We examined how supplementation with marine omega-3 fatty acids and evening primrose oil (rich in GLA) could help relieve rheumatoid arthritis symptoms in a randomized trial of 60 patients.

After 12 weeks, those taking either fish oil alone or in combination with evening primrose oil showed remarkable improvements in joint pain and disease activity compared to those who received no supplements.

This suggests that these oils may significantly benefit people dealing with the inflammation and discomfort of rheumatoid arthritis.
7
Evening primrose oil shows symptom relief
We explored the impact of evening primrose oil (EPO) on rheumatoid arthritis (RA) in a double-blind, placebo-controlled study involving 49 patients. Participants took EPO or EPO combined with fish oil, with the aim of reducing reliance on non-steroidal anti-inflammatory drugs (NSAIDs).

After 12 months, those on EPO noted significant improvements and were able to cut back on their NSAIDs. However, once they switched to placebo, they relapsed, revealing that while EPO may improve symptoms, it doesn't change the underlying disease. Thus, it appears evening primrose oil can help manage RA symptoms and lessen NSAID use, but it doesn’t modify the disease itself.
4
Evening primrose oil shows mild effect
We looked into how evening primrose oil might help relieve symptoms of rheumatoid arthritis in a study involving 40 patients over six months. Patients were split into two groups: one received evening primrose oil, while the other got a placebo.

While there were mild improvements in morning stiffness for those taking evening primrose oil, olive oil actually showed a more significant reduction in pain over time. Therefore, evening primrose oil may offer some benefits, but olive oil revealed notable advantages that shouldn't be overlooked.
We examined the latest insights into herbal therapies for rheumatoid arthritis, including evening primrose oil. Our analysis included 22 studies, revealing moderate evidence suggesting that gamma linolenic acid (GLA), found in evening primrose oil, may ease pain and disability related to RA.

However, while some benefits were noted, the evidence remains mixed and the risk of side effects should not be overlooked. More comprehensive studies are needed to firmly establish its effectiveness for RA treatment.

References

  1. Veselinovic M, Vasiljevic D, Vucic V, Arsic A, Petrovic S, et al. Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. Nutrients. 2017;9. doi:10.3390/nu9040325
  2. El-Sayed RM, Moustafa YM, El-Azab MF. Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1. Inflammopharmacology. 2014;22:305. doi:10.1007/s10787-014-0200-5
  3. Montserrat-de la Paz S, García-Giménez MD, Ángel-Martín M, Pérez-Camino MC, Fernández Arche A. Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages. J Ethnopharmacol. 2014;151:131. doi:10.1016/j.jep.2013.10.012
  4. Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst Rev. 2011. doi:10.1002/14651858.CD002948.pub2
  5. Brzeski M, Madhok R, Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol. 1991;30:370.
  6. Belch JJ, Ansell D, Madhok R, O'Dowd A, Sturrock RD. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. Ann Rheum Dis. 1988;47:96.
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